Human Oral Microbiota’s Response to Antimicrobial Properties of Honey

International Journal of Agriculture & Environmental Science
© 2024 by SSRG - IJAES Journal
Volume 11 Issue 1
Year of Publication : 2024
Authors : Yamani Hanaa Abbas, Fagera Bayan Mohammed
pdf
How to Cite?

Yamani Hanaa Abbas, Fagera Bayan Mohammed, "Human Oral Microbiota’s Response to Antimicrobial Properties of Honey," SSRG International Journal of Agriculture & Environmental Science, vol. 11,  no. 1, pp. 7-14, 2024. Crossref, https://doi.org/10.14445/23942568/IJAES-V11I1P102

Abstract:

The human oral microbiome is important under both healthy and diseased conditions. Temporary intruders, protective bacteria, and opportunistic pathogens of oral cavity niches form the oral microbiome. Most oral microorganisms are commensal and regulate the balance of the oral biological community. However, some microbes are associated with periodontitis and dental caries. Honey applications are known to cure minor (flu or cold) and severe ailments (burns, gastrointestinal, liver, and cardiovascular issues) and exert antimicrobial activities against viruses and bacteria. This study involved microbiological and molecular approaches to evaluate honey’s antimicrobial properties against human oral cavity pathogens without disturbing oral microbiota equilibrium. The potential use of honey as a mouthwash was assessed as well. The results revealed the effective antimicrobial potential of Manuka and Sidr honey compared to the control group. The study also confirmed that honey-based natural mouthwash could serve as an efficient alternative to chemical mouthwash.

Keywords:

Honey, Antimicrobial activity, Oral microbiome, Mouthwash, Dental caries, and Periodontitis.

References:

[1] Jeffrey I. Gordon, and Todd R. Klaenhammer, “A Rendezvous with Our Microbes,” Proceedings of the National Academy of Sciences, vol. 108, pp. 4513-4515, 2011.
[CrossRef] [Google Scholar] [Publisher Link]
[2] Amer Abdrazak Mohamed, “Investigation of the Microbiological Profile of Oral Leukoplakia,” PhD thesis, Trinity College Dublin School of Dental Sciences, 2019.
[Google Scholar] [Publisher Link]
[3] Juliana Vianna Pereira et al., “Bacterial Diversity in the Saliva of Patients with Different Oral Hygiene Indexes,” Brazilian Dental Journal, vol. 23, no. 4, pp. 409-416, 2012.
[CrossRef] [Google Scholar] [Publisher Link]
[4] Pierre Le Bars et al., “The Oral Cavity Microbiota: Between Health, Oral Disease, and Cancers of the Aerodigestive Tract,” Canadian Journal of Microbiology, vol. 63, no. 6, pp. 475-492, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[5] Ivan Nasidze et al., “Global Diversity in the Human Salivary Microbiome,” Genome Research, vol. 19, no. 4, pp. 636-643, 2009.
[CrossRef] [Google Scholar] [Publisher Link]
[6] L.M.C. Collins, and C. Dawes, “The Surface Area of the Adult Human Mouth and Thickness of the Salivary Film Covering the Teeth and Oral Mucosa,” Journal of Dental Research, vol. 66, no. 8, pp. 1300-1302, 1987.
[CrossRef] [Google Scholar] [Publisher Link]
[7] Alastair J. Wilson, and Daniel H. Nussey, “What is Individual Quality? An Evolutionary Perspective,” Trends in Ecology and Evolution, vol. 25, no. 4, pp. 207-214, 2010.
[CrossRef] [Google Scholar] [Publisher Link]
[8] Lakshman Samaranayake, and Victor H. Matsubara, “Normal Oral Flora and the Oral Ecosystem,” Dental Clinics, vol. 61, no. 2, pp. 199- 215, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[9] Floyd E. Dewhirst et al., “The Human Oral Microbiome,” Journal of Bacteriology, vol. 192, no. 19, pp. 5002-5017, 2010.
[CrossRef] [Google Scholar] [Publisher Link]
[10] A.H. Fjallman, “Protection of Dental Health Using Honey with High Antibacterial Activity,” M.Sc. Thesis, University of Waikato, 2000.
[Google Scholar]
[11] W.M. Edgar, and G.N. Jenkins, “Solubility-Reducing Agents in Honey and Partly-Refined Crystalline Sugar,” British Dental Journal, vol. 136, no. 7, pp.7-14, 1974.
[CrossRef] [Google Scholar] [Publisher Link]
[12] Frank A. Scannapieco, “The Oral Microbiome: Its Role in Health and in Oral and Systemic Infections,” Clinical Microbiology Newsletter, vol. 35, no.20, pp. 163-169, 2013.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Frederick Kavanagh, CHAPTER 3 - Dilution Methods of Antibiotic Assays, Analytical Microbiology, Academic Press, pp. 125-140, 1963.
[CrossRef] [Google Scholar] [Publisher Link]
[14] M. Andrea Azcárate-Peril, and Raúl R. Raya, Methods for Plasmid and Genomic DNA Isolation from Lactobacilli, Food Microbiology Protocols, Humana Press, vol. 14, pp. 135-139, 2001.
[CrossRef] [Google Scholar] [Publisher Link]
[15] Jacqueline Abranches et al., “Biology of Oral Streptococci,” Microbiology Spectrum, vol. 6, no. 5, pp. 1110-1128, 2018.
[CrossRef] [Google Scholar] [Publisher Link]
[16] Getahun Temesgen et al., “Evaluation of Chlorination Efficiency on Improving Microbiological and Physicochemical Parameters in Water Samples Available in Sheble Berenta District Amhara Region,” Applied Water Science, vol. 13, no. 5, pp. 1-8, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[17] Ahmed G. Hegazi et al., “Antibacterial and Antioxidant Activities of Some Saudi Arabia Honey Products,” Iranian Journal of Medical Microbiology, vol. 14, no. 5, pp. 490-500, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[18] Prathibha Anand Nayak, Ullal Anand Nayak, and Vishal Khandelwal, “The Effect of Xylitol on Dental Caries and Oral Flora,” Clinical, Cosmetic and Investigational Dentistry, vol. 6, pp. 89-94, 2014.
[Google Scholar] [Publisher Link]
[19] Peter J. Taormina, Brendan A. Niemira, and Larry R. Beuchat, “Inhibitory Activity of Honey Against Foodborne Pathogens as Influenced by the Presence of Hydrogen Peroxide and Level of Antioxidant Power,” International Journal of Food Microbiology, vol. 69, no. 3, pp. 217-225, 2001.
[CrossRef] [Google Scholar] [Publisher Link]
[20] A.M. Alqurashi, A.E. Masoud, and A.M. Alamin, “Antibacterial Activity of Saudi Honey against Gram Negative Bacteria,” Journal of Microbiology and Antimicrobials, vol. 5, no. 1, pp. 1-5, 2013.
[CrossRef] [Google Scholar] [Publisher Link]
[21] Richa Singhal et al., “Effectiveness of Three Mouthwashes Manuka Honey, Raw honey, and Chlorhexidine on Plaque and Gingival Scores of 12–15-Year-Old School Children: A Randomized Controlled Field Trial,” Journal of Indian Society of Periodontology, vol. 22, no. 1 pp. 34-39, 2018.
[CrossRef] [Google Scholar] [Publisher Link]