Giant cell tumour of the sternum-Two cases

International Journal of Medical Science

© 2016 by SSRG - IJMS Journal

Volume 3 Issue 3

Year of Publication : 2016

Authors : Nishaa.P, Raghuram.P, Navin patil, Jaipal B.R and Akkamahadevi patel

10.14445/23939117/IJMS-V3I3P101

How to Cite?

Nishaa.P, Raghuram.P, Navin patil, Jaipal B.R and Akkamahadevi patel, "Giant cell tumour of the sternum-Two cases," SSRG International Journal of Medical Science, vol. 3,  no. 3, pp. 1-3, 2016. Crossref, https://doi.org/10.14445/23939117/IJMS-V3I3P101

Abstract:

Giant cell tumor (GCT) is a common, benign, locally aggressive bone tumour affecting long bones patients between the ages of 20 and 45 years. The incidence of this tumour is 5%. Multinucleate giant cells identify it, which consists of more than 100 nuclei and fibrous stroma. Amongst long bones the tibia and femur are affected. Other affected sites are radius, small bones of hand, sacrum, pelvis, vertebral bodies and ribs. The sternum is a flat bone. The commonest tumour affecting sternum is metastasis. Most common tumours affecting sternum are chondrosarcoma, osteosarcoma, myeloma, and lymphoma. Benign primary tumors of the sternum are even rarer than malignant primary tumors of the sternum. Giant Cell Tumour of the sternum is a rare condition and to the best of our knowledge only seven cases are documented in the literature. We are presenting case reports of two patients who presented with sternal mass pathologically proven as giant cell tumour. One patient is a 38-year-old woman and another 28-year-old aged man. These patients presented with palpable chest wall masses. Plain radiographs showed an expansile osteolytic lesion of the sternum. Computed tomography (CT) demonstrated focal cortical bone lytic lesion with destruction, soft tissue extension. Bone scan showed increase uptake. Fine needle aspiration cytology examination performed revealed a benign tumor composed of multi-nucleated giant cells compatible with a Giant Cell tumour .Histopathological analysis showed presence of multinucleated giant cells, and spindle cells with elongated nuclei without atypias although rare giant cell tumour of sternum must be considered as a differential in patients with lytic expansile lesion of sternum.

Keywords:

Giant cell tumour of sternum, Osteoclastoma, Sternal tumours, CECT, Sternum, Osteoclasts.

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