Constituents of the ethanolic extract of Bryophyllum Pinnatum leaves

International Journal of Applied Chemistry

© 2016 by SSRG - IJAC Journal

Volume 3 Issue 1

Year of Publication : 2016

Authors : Jack, I. R. and Nwachoko, N

10.14445/23939133/IJAC-V3I1P101

How to Cite?

Jack, I. R. and Nwachoko, N, "Constituents of the ethanolic extract of Bryophyllum Pinnatum leaves," SSRG International Journal of Applied Chemistry, vol. 3,  no. 1, pp. 1-4, 2016. Crossref, https://doi.org/10.14445/23939133/IJAC-V3I1P101

Abstract:

Bryophyllum Pinnatum commonly called cant bury bells of the family crassulaceae is a perennial herb. Soxhlet extraction of the fresh leaves with ethanol and chromatography of the crude gave two compounds – a pungent oil (1) Rf 0.75 identified as 4-ethoxy-cyclopent-2-enone and another oil (3) Rf 0.52 also identified as 2,5-dimethoxyfuran by their spectra data such as infra red, mass and proton magnetic resonance spectra. The structure of (3) was further confirmed by synthesis by the oxidation of furan(2) with bromine in methanol and comparing the spectra of the synthetic compound with those of the naturally occurring compound. A significant feature of (3) is that it is a mixture of two isomers with H-2 and H-5 protons appearing as singlets at δ6.00 and 5.91. The two methoxy groups also appeared as two singlets at δ3.32 and 3.28.

Keywords:

Bryophyllum Pinnatum, soxhlet extraction, 4-ethoxy-cyclopent-2-enone and 2,5- dimethoxyfuran

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