Effect of Organic Solvent Dielectric Constant on Protonation Equilibria of Phenylalanine and Maleic acid

International Journal of Applied Chemistry

© 2016 by SSRG - IJAC Journal

Volume 3 Issue 1

Year of Publication : 2016

Authors : T. Sreevaram, A.V.R. Gajapathi Raju, N. Vijaya Kumar, B.B.V. Sailaja

10.14445/23939133/IJAC-V3I4P101

How to Cite?

T. Sreevaram, A.V.R. Gajapathi Raju, N. Vijaya Kumar, B.B.V. Sailaja, "Effect of Organic Solvent Dielectric Constant on Protonation Equilibria of Phenylalanine and Maleic acid," SSRG International Journal of Applied Chemistry, vol. 3,  no. 1, pp. 5-9, 2016. Crossref, https://doi.org/10.14445/23939133/IJAC-V3I4P101

Abstract:

The protonation constants of Phenylalanine and Maleic acid have been studied pH metrically in various concentrations (0-60%v/v) of acetonitrile-water mixtures maintaining an ionic strength of 0.16 mol L-1 at 303K. The protonation constants have been calculated with the computer program MINIQUAD75 and are selected based on statistical parameters. Linear variation and non linear variation of step-wise protonation constants (log K) with reciprocal of dielectric constant of the solvent mixture has been attributed to the dominance of the electrostatic and non-electrostatic forces respectively.

Keywords:

Protonation constants, Phenylalanine, Maleic acid, Acetonitrile, MINIQUAD75

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