This study presents the preparation, purifica- tion, identification and applications of Manganese (II) phthalocyanine complex. Non-solvent method was used for the preparation of the complex at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria.

"/> This study presents the preparation, purifica- tion, identification and applications of Manganese (II) phthalocyanine complex. Non-solvent method was used for the preparation of the complex at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria.

"/> This study presents the preparation, purifica- tion, identification and applications of Manganese (II) phthalocyanine complex. Non-solvent method was used for the preparation of the complex at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria.

"/> This study presents the preparation, purifica- tion, identification and applications of Manganese (II) phthalocyanine complex. Non-solvent method was used for the preparation of the complex at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria.

"/>

Call for Paper - Upcoming Issues

Preparation, Characterization and Biological Activity Study of Manganese (II) Phthalocyanine Complex

International Journal of Applied Chemistry
© 2019 by SSRG - IJAC Journal
Volume 6 Issue 1
Year of Publication : 2019
Authors : Aziza. A. K
10.14445/23939133/IJAC-V6I1P103
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How to Cite?

Aziza. A. K, "Preparation, Characterization and Biological Activity Study of Manganese (II) Phthalocyanine Complex," SSRG International Journal of Applied Chemistry, vol. 6,  no. 1, pp. 19-23, 2019. Crossref, https://doi.org/10.14445/23939133/IJAC-V6I1P103

Abstract:

This study presents the preparation, purifica- tion, identification and applications of Manganese (II) phthalocyanine complex. Non-solvent method was used for the preparation of the complex at high temperature (sand bath technique). Phthalic anhydride was used as a precursor for the preparation. Characterization of as-synthesized complex was carried out by different instrumentation methods including ultraviolet-visible, infrared, mass spectroscopy, elemental and thermaogravimetric analyses. Magnetic susceptibility of the studied complex was also determined. Antimicrobial activities of the tested compound were carried out using bacteria and fungi. Human heptacellular Carcinoma (Hep-G2) was used for studying the complex antitumor activity. The results of characterization showed that the complex was prepared and separated in a pure form whereas, the biological activity data depicted that the complex has valuable activity against cell line (Hep-G2) and bacteria.

Keywords:

Manganese (II) Phthalocyanine, Non-solvent method, Biological activity, (Hep-G2) cell.

References:

[1] Moser, F. H and Thomas, A. L. (1963). Phthalocyanines Compounds, Rehinhold Publishing Corporation, New York.
[2] Leznoff, C. C., Lever, A. B. P. (1989). Phthalocyanines, Properties and Applications,1, VCH Publications, Inc; New York.
[3] Gregory, P. (2000). Industrial applications of phthalocyanines, Journal of Porphyrins and Phthalocyanines 4: 432- 437.
[4] Puddephatt. RJ. Advances in organometallic polymers, ring-opening polymerization and the
[5] self-assembly of supramolecular polymers. Journal of Inorganic and Organometalic Polymer. Material.;15, 371–88, (2005).
[6] AS.Abd-El-Aziz, Carraher Jr CE, Pittman Jr CU, M. Zeldin “Macromolecules containing metal and metal-like elements”.
Wiley-Interscience, John Wiley & Sons, Inc ; New York, (2003–2007).
[7] Gregory, P. (2000). Industrial applications of phthalocyanines, Journal of Porphyrins and Phthalocyanines 4: 432- 437.
[8] Leznoff, C. C., Lever, A. B. P. (1986– 1993). The Phthalocyanines: Properties and Applications, 1–4, John Wiley and Sons Inc; New York
[9] Myers, J. F., Canham, G. W. R. and Lever, A. B. P. (1975). Inorganic Chemistry 14: 461-468.
[10] Moser, F. H and Thomas, A. L. (1983). The Phthalocyanines , 1–2, CRC Press, FL.
[11] Dent C. E., Linstead R. P. and Lowe A. R. (1934). The structure of the phthalocyanines, Journal of Chemical Society 1934: 1033-1039.
[12] Myers, J. F., Canham, G. W. R. and Lever, A. B. P. (1975). Inorganic Chemistry 14: 461-468.
[13] Kobayashi, N. and Opin, C. (1999). Phthalocyanines, Journal of Solid.
[14] Leznoff, C. C. and Lever, A.B.P. (1989). Phthalocyanines Properties and Applications, VCH,Weinheim.
[15] Gerdes, R. W., orhle, D., Spiller, W., Schneider, G., Schnurpfeil, G. and Schulz- Ekloff, G. (1997). Photo-oxidation of phenol and monochlorophenols in oxygen saturated aqueous solutions by different photosen-sitizers, Journal of Photochemistry and Photobiology A Chemistry 111: 65-74.
[16] Snow, A. W., Shirk, J. S. and Pong, R. G. S. (2000). Oligo oxyethylene liquid phthalocyanines, Journal of Porphyrins and Phthalocyanines 4: 518-524.
[17] Liu, S. G., Liu, Y. Q, Xu, Y., Zhu, D. B., Yu, A. C. and Zhao, X. S. (1998). Synthesis, Langmuir−Blodgett Film, and Second-Order Nonlinear Optical Property of a Novel Asymmetrically Substituted Metal-Free Phthalocyanine, Langmuir 14: 690-695.
[18] Hirth, A.G. amd Trp,nacj. N.(1999). Efficient near-IR sensitization of nanocrystalline TiO2 films by zinc and aluminum Phthalocyanines. Journal of Porphyrins and Phthalaoyanines 3:230-37.
[19] Mac Donald, I.J. and Dougherty, T.J. (2001). Basic Principles of Photo dynamictherrpy Journal of Prophyrins and Phthalocyanines.5:105-129.
[20] W.X. Chen, W.Y. Lu, Y.Y. Yao, M.H. Xu, (2007). Journal of Enviromental. Science. Technology 41: 6240.
[21] Ali, H., Van Lier, J. E. (1999). Metal complexes as photo- and radiosensitizers. Chemical, Reviews 99:2379-2450.
[22] Nyokong, T. (2007). Effects of substituents on the photochemical and photophysical properties of non-transition metal phthalocyanines. Coordination Chemistry Reviews 251: 1707-1722.
[23] Ng, D. K. P. (2003). Dendritic phthalocyanines: synthesis, photophysical properties, and aggregation behavior. Comptes Rendus Chimie 6: 903-910.
[24] Achar, B. N., Fohlen, G. M. and Parker, J. A. (1987). Organic semiconductors-metal phthalocyanine sheet polymers. Journal of Polymer Science Part a 25:443-450.
[25] A.W. Bauer, W.M. Kirby, C. Sherris, M. Turack, , (1966). Antibiotic susceptibility testing by a standardized single disk method, American Journal of Clinical Pathology 45: 493-496
[26] National Committee for Clinical Laboratory Standards. (1993) Performance VOL.41,(1997) antimicrobial susceptibility of Flavobacteria.
[27] T.Mosmann, (1983).Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunology Methods 65: 55-63.
[28] P.Vijayan, C. Raghu, S.A. Dhanaraj, B. Suresh, (2004).Antiviral activity of medicinal plants of Nilgiris. Indian Journal of Medical. Research; 120, 24-29.
[29] A.M.Schaffer, M. Gouterman, E.R. Davidson, (1973) Theoretica Chimica Acta; 30 9.
[30] A.B.P.Lever, (1965).Advances in Inorganic Chemistry and Radiochemistry; 7, 27.