The Effect of the Water Extract of Soybean Seeds in Two Different Doses on Hyperthyroidism

International Journal of Agriculture & Environmental Science

© 2020 by SSRG - IJAES Journal

Volume 7 Issue 1

Year of Publication : 2020

Authors : Ghada Rafik Hasan, Hiam Kamel Fadel

10.14445/23942568/IJAES-V7I1P111

How to Cite?

Ghada Rafik Hasan, Hiam Kamel Fadel, "The Effect of the Water Extract of Soybean Seeds in Two Different Doses on Hyperthyroidism," SSRG International Journal of Agriculture & Environmental Science, vol. 7,  no. 1, pp. 56-61, 2020. Crossref, https://doi.org/10.14445/23942568/IJAES-V7I1P111

Abstract:

The study was conducted to determine the effect of the water extract of soybean seeds on the levels of FT3 and FT4 in the serum of adult Albino mice in which hyperthyroidism was introduced, and to highlighting its therapeutic efficacy.
The study included 40 Albino mice belonging to the strain "Balb / c". Mice were distributed into four experimental groups (10 mice in each group).
The first group was the physiological control. It was dose with 0.9% Nacl as a physiological solution until the end of the experiment. The second group was a pathological control that was administered with Levoteroxin LT4 at a dose of 100 μg / 100 g for 10 consecutive days.
Whereas, the third and fourth groups were treated with 300 mg / kg and 500 mg / kg, respectively, from the extract of the water soybean seed after introducing hyperactivity for four consecutive weeks. At the end of the dose period, animals were drugged, and blood samples were drawn by stabbing the heart.
Results showed that the soybean seed extract can be considered a natural treatment for hyperthyroidism. The effect of the 300 mg / kg dose was more effective compared to the effect of the 500 mg / kg dose.

Keywords:

Hyperthyroidism, water extract, soybean seeds, FT4 and FT.

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