Enhanced Automated Breast Cancer Diagnostics System Using Deep Transfer Learning Techniques on Histopathological Images

International Journal of Electronics and Communication Engineering
© 2025 by SSRG - IJECE Journal
Volume 12 Issue 2
Year of Publication : 2025
Authors : V. Nirmalrani, J. Jaganpradeep, R. Prathipa, A. BalaMurali, T. A. Mohanaprakash, D. Daya Florance
pdf
How to Cite?

V. Nirmalrani, J. Jaganpradeep, R. Prathipa, A. BalaMurali, T. A. Mohanaprakash, D. Daya Florance, "Enhanced Automated Breast Cancer Diagnostics System Using Deep Transfer Learning Techniques on Histopathological Images," SSRG International Journal of Electronics and Communication Engineering, vol. 12,  no. 2, pp. 120-127, 2025. Crossref, https://doi.org/10.14445/23488549/IJECE-V12I2P111

Abstract:

As breast cancer continues to be the leading cause of death among women around the world, there is an urgent need for diagnostic tools that are efficient, accurate, and automated. The purpose of this research is to develop an Automated Breast Cancer Diagnostics System that makes use of deep transfer learning techniques on histopathology pictures. The system makes use of deep transfer learning techniques like ResNet, EfficientNet, and VGG-19 Net that integrate Global Average Pooling (GAP) layers in order to reduce the amount of time complexity and processing overhead without affecting the accuracy of the results. Traditional fully connected layers are replaced by GAP layers, significantly reducing the number of trainable parameters while preserving powerful feature extraction capabilities. Evaluation of the proposed system is carried out using the Breast Cancer Histopathological Image (BACH) dataset. This dataset comprises high-resolution microscopic images classified into benign, malignant, and normal tissue types. The results of the experiments show that the system obtains an accuracy of 96.7% and an F1-score of 96.3, which is higher than the baseline models. When compared to standard fully connected architectures, the inclusion of GAP layers results in a reduction in the computational cost, which in turn leads to training periods that are 35% faster.

Keywords:

Breast cancer, Disease prediction, Tumor disease, Histopathology Images, Global average pooling, Deep learning model, Transfer learning and disease classification.

References:

[1] Mohammed Amine Naji et al., “Machine Learning Algorithms for Breast Cancer Prediction and Diagnosis,” Procedia Computer Science, vol. 191, pp. 487-492, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[2] Arpita Joshi, and Dr. Ashish Mehta, “Comparative Analysis of Various Machine Learning Techniques for Diagnosis of Breast Cancer,” International Journal on Emerging Technologies, vol. 8, no. 1, pp. 522-526, 2017.
[Google Scholar] [Publisher Link]
[3] Hiba Asri et al., “Using Machine Learning Algorithms for Breast Cancer Risk Prediction and Diagnosis,” Procedia Computer Science, vol. 83, pp. 1064-1069, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[4] Danqing Ma et al., “Implementation of Computer Vision Technology Based on Artificial Intelligence for Medical Image Analysis,” International Journal of Computer Science and Information Technology, vol. 1, no. 1, pp. 69-76, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[5] Gabor Cserni, “Histological Type and Typing of Breast Carcinomas and the WHO Classification Changes Over Time,” Pathologica, vol. 112, no. 1, pp. 25-41, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[6] Lazaros Tsochatzidis et al., “Integrating Segmentation Information into CNN for Breast Cancer Diagnosis of Mammographic Masses,” Computer Methods and Programs in Biomedicine, vol. 200, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[7] S. R. Sannasi Chakravarthy, N. Bharanidharan, and Harikumar Rajaguru, “Multi-Deep CNN based Experimentations for Early Diagnosis of Breast Cancer,” IETE Journal of Research, vol. 69, no. 10, pp. 7326-7341, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[8] A. D. Belsare et al., “Classification of Breast Cancer Histopathology Images using Texture Feature Analysis,” TENCON - IEEE Region 10 Conference, Macao, China, pp. 1-5, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[9] Fabio A. Spanhol et al., “Deep Features for Breast Cancer Histopathological Image Classification,” IEEE International Conference on Systems, Banff, AB, Canada, pp. 1868-1873, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[10] Fei Zhang et al., “Enhanced Breast Cancer Classification through Data Fusion Modeling,” Journal of Theory and Practice of Engineering Science, vol. 4, no. 1, pp. 79-85, 2024.
[CrossRef] [Google Scholar] [Publisher Link]
[11] Fabio Alexandre Spanhol et al., “Breast Cancer Histopathological Image Classification using Convolutional Neural Networks,” International Joint Conference on Neural Networks, Vancouver, BC, Canada, pp. 2560-2567, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[12] Neslihan Bayramoglu, Juho Kannala, and Janne Heikkila, “Deep Learning for Magnification Independent Breast Cancer Histopathology Image Classification,” 23rd International Conference on Pattern Recognition, Cancun, Mexico, pp. 2440-2445, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Adrienne G. Waks, and Eric P. Winer, “Breast Cancer Treatment: A Review,” Jama-Journal of the American Medical Association, vol. 321, no. 3, pp. 288-300, 2019.
[Google Scholar] [Publisher Link]
[14] Gousia Habib, and Shaima Qureshi, “GAPCNN with HyPar: Global Average Pooling Convolutional Neural Network with Novel NNLU Activation Function and HYBRID Parallelism,” Frontiers in Computational Neuroscience, vol. 16, pp. 1-18, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[15] Fabio A. Spanhol et al., “A Dataset for Breast Cancer Histopathological Image Classification,” IEEE Transactions on Biomedical Engineering, vol. 63, no. 7, pp. 1455-1462, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[16] C. Tamilselvi et al., “Breast Cancer Prediction Using a Deep Learning Algorithm on the Cloud Medical Data,” International Conference on Self Sustainable Artificial Intelligence Systems, Erode, India, pp. 414-419, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[17] I. Jaichitra et al., “Deep Learning for Breast Cancer Prediction in the Era of Big Data: A Comparative Study of Gene Expression and DNA Methylation,” International Conference on Sustainable Communication Networks and Application, Theni, India, pp. 222-229, 2023.
[CrossRef] [Google Scholar] [Publisher Link]