Reliable Detection of Polycystic Ovary Syndrome Using a Hybrid Deep Learning Approach: CNN-LSTM-GRU Integration

International Journal of Electrical and Electronics Engineering
© 2025 by SSRG - IJEEE Journal
Volume 12 Issue 3
Year of Publication : 2025
Authors : Sruthi SanilKumar
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How to Cite?

Sruthi SanilKumar, "Reliable Detection of Polycystic Ovary Syndrome Using a Hybrid Deep Learning Approach: CNN-LSTM-GRU Integration," SSRG International Journal of Electrical and Electronics Engineering, vol. 12,  no. 3, pp. 155-169, 2025. Crossref, https://doi.org/10.14445/23488379/IJEEE-V12I3P116

Abstract:

Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal disorder in women of reproductive age categorized by the presence of numerous tiny cysts on the ovaries, greater levels of androgen and irregular menstrual cycles. PCOS detection involves identifying and categorizing ovarian health conditions employing medical imaging modalities. Accurate detection is essential for appropriate treatment and inhibition of related health problems. Challenges such as the intrinsic complexity of ovarian morphological characteristics and differences in image quality due to transformations in acquisition settings or noise significantly affect the accuracy of detection systems. Conventional methods severely depend on manual image examination and feature extraction, often leading to variations and limited reliability. This research focuses on creating a hybrid Deep Learning (DL) system for the unfailing detection of PCOS employing ultrasound images. The system was assessed on the Kaggle PCOS dataset containing 3,856 images categorized into "infected" and "not infected" cases. Preprocessing and data augmentation techniques were utilized to increase variability in data, followed by feature extraction operating the hybrid model. The proposed system merges Convolutional Neural Network (CNN), Gated Recurrent Unit (GRU) and Long Short-Term Memory (LSTM) architectures to collect spatial and temporal features expertly. The system achieved outstanding results with an accuracy of 98.50%, precision of 98.59%, recall of 98.55% and an F1 score of 98.48%. These results underscore the efficacy of the hybrid framework in responding to the challenges of PCOS detection, providing an efficient and better solution for clinical applications.

Keywords:

Polycystic Ovary Syndrome, Deep Learning, Convolutional Neural Network, Ultrasound image, Long Short-Term Memory, Gated Recurrent Unit.

References:

[1] Nithya Sathiadhas Puvaneswari, “Detection of Polycystic Ovarian Syndrome using Convolutional Neural Network in Conjunction with Transfer Learning Models,” Master’s Thesis, Dublin, National College of Ireland, 2022.
[Google Scholar] [Publisher Link]
[2] Mohamed Abouhawwash et al., “Automatic Diagnosis of Polycystic Ovarian Syndrome Using Wrapper Methodology with Deep Learning Techniques,” Computer Systems Science and Engineering, vol. 47, no. 1, pp. 239-253, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[3] Sayma Alam Suha, and Muhammad Nazrul Islam, “An Extended Machine Learning Technique for Polycystic Ovary Syndrome Detection Using Ovary Ultrasound Image,” Scientific Reports, vol. 12, no. 1, pp. 1-16, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[4] Tahsin Istiyaq et al., “Polycystic Ovary Syndrome Detection Using Neural Network,” Doctoral Dissertation, Brac University, pp. 1-34, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[5] Zahra Zad et al., “Predicting Polycystic Ovary Syndrome with Machine Learning Algorithms from Electronic Health Records,” Frontiers in Endocrinology, vol. 15, pp. 1-14, 2024.
[CrossRef] [Google Scholar] [Publisher Link]
[6] Jiekee Lim et al., “Machine Learning Classification of Polycystic Ovary Syndrome Based on Radial Pulse Wave Analysis,” BMC Complementary Medicine and Therapies, vol. 23, no. 1, pp. 1-15, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[7] Harshita Batra, and Leema Nelson, “DCADS: Data-Driven Computer Aided Diagnostic System using Machine Learning Techniques for Polycystic Ovary Syndrome,” International Journal of Performability Engineering, vol. 19, no. 3, pp. 193-202, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[8] Sayma Alam Suha, and Muhammad Nazrul Islam, “Exploring the Dominant Features and Data-Driven Detection of Polycystic Ovary Syndrome through Modified Stacking Ensemble Machine Learning Technique,” Heliyon, vol. 9, no. 3, pp. 1-21, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[9] Piyush Bhardwaj, and Parul Tiwari, “Manoeuvre of Machine Learning Algorithms in Healthcare Sector with Application to Polycystic Ovarian Syndrome Diagnosis,” Proceedings of Academia-Industry Consortium for Data Science, Springer, Singapore, pp. 71-84, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[10] P. Rakshitha Kiran, and N.C. Naveen, “Op-RMSprop (Optimized-Root Mean Square Propagation) Classification for Prediction of Polycystic Ovary Syndrome (PCOS) Using Hybrid Machine Learning Technique,” International Journal of Advanced Computer Science and Applications, vol. 13, no. 6, pp. 588-596, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[11] Pijush Dutta, Shobhandeb Paul, and Madhurima Majumder, “An Efficient SMOTE Based Machine Learning Classification for Prediction & Detection of PCOS,” pp. 1-14, 2021.
[Google Scholar]
[12] Subrato Bharati et al., “Ensemble Learning for Data-Driven Diagnosis of Polycystic Ovary Syndrome,” 21st International Conference on Intelligent Systems Design and Applications, Springer, Cham, pp. 1250-1259, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Neha A. Ranjith Kumar, and Vijayakumar Varadarajan, “Hybrid PCOS Net: A Synergistic CNN-LSTM Approach for Accurate Polycystic Ovary Syndrome Detection,” pp. 1- 36, 2024.
[Google Scholar]
[14] S. Sowmiya et al., “F-Net: Follicles Net an Efficient Tool for the Diagnosis of Polycystic Ovarian Syndrome Using Deep Learning Techniques,” PLOS one, vol. 19, no. 8, pp. 1-21, 2024.
[CrossRef] [Google Scholar] [Publisher Link]
[15] Abrar Alamoudi et al., “A Deep Learning Fusion Approach to Diagnosis the Polycystic Ovary Syndrome (PCOS),” Applied Computational Intelligence and Soft Computing, vol. 2023, no. 1, pp. 1-15, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[16] Junfang Fan et al., “Accurate Ovarian Cyst Classification with a Lightweight Deep Learning Model for Ultrasound Images,” IEEE Access, vol. 11, pp. 110681-110691, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[17] Wenqi Lv et al., “Deep Learning Algorithm for Automated Detection of Polycystic Ovary Syndrome Using Scleral Images,” Frontiers in Endocrinology, vol. 12, pp. 1-8, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[18] A.K.M. Salman Hosain, Md Humaion Kabir Mehedi, and Irteza Enan Kabir, “PCONET: A Convolutional Neural Network Architecture to Detect Polycystic Ovary Syndrome (PCOS) from Ovarian Ultrasound Images,” IEEE International Conference on Engineering and Emerging Technologies, Kuala Lumpur, Malaysia, pp. 1-6, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[19] Srivastava, S., Kumar, P., Chaudhry, V., & Singh, A. (2020). “Detection of Ovarian Cyst in Ultrasound Images Using Fine-Tuned VGG 16 Deep Learning Network,” SN Computer Science, vol. 1, no. 2, pp. 1-8, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[20] Anagha Choudhari, PCOS Detection Using Ultrasound Images, Kaggle.com, 2022. [Online] Available: https://www.kaggle.com/datasets/anaghachoudhari/pcos-detection-using-ultrasound-images/data
[21] Md Zahangir Alom et al., “A State-of-the-Art Survey on Deep Learning Theory and Architectures,” Electronics, vol. 8, no. 3, pp. 1-66, 2019.
[CrossRef] [Google Scholar] [Publisher Link]
[22] Iram Bibi et al., “A Dynamic DL-Driven Architecture to Combat Sophisticated Android Malware,” IEEE Access, vol. 8, pp. 129600 129612, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[23] Salma Alhagry, Aly Aly Fahmy, and Reda A. El-Khoribi, “Emotion Recognition based on EEG using LSTM Recurrent Neural Network,” International Journal of Advanced Computer Science and Applications, vol. 8, no. 10, pp. 355-358, 2017.
[CrossRef] [Google Scholar] [Publisher Link]