Diabetes Insipidus in Sepsis

International Journal of Medical Science

© 2015 by SSRG - IJMS Journal

Volume 2 Issue 1

Year of Publication : 2015

Authors : Dr. S.Theophilus Ved Bhushan, Dr Muneer A Mulla, Dr Haroonrasid and Dr Chandrashekhar D.M.

10.14445/23939117/IJMS-V2I1P101

How to Cite?

Dr. S.Theophilus Ved Bhushan, Dr Muneer A Mulla, Dr Haroonrasid and Dr Chandrashekhar D.M., "Diabetes Insipidus in Sepsis," SSRG International Journal of Medical Science, vol. 2,  no. 1, pp. 1-8, 2015. Crossref, https://doi.org/10.14445/23939117/IJMS-V2I1P101

Abstract:

Sepsis is defined as a clinical condition in which there is systemic inflammatory response syndrome co-exists with a clearly established focus of infection. Diabetes insipidus is a disease condition in which there is a large amount of free water excreted in urine. A 24 hour urine volume is more than 50 ml / kg / hour and the urinary osmolality is less than 300 mosmol/L and the urine has low specific gravity. The association of diabetes insipidus (DI) and sepsis is not uncommon but often it is overlooked.

Keywords:

Diabetes Insipidus , Sepsis.

References:

[1]Robinson  AL,  Verbalis JG, Posterior Pituitary In Kronberg HM, Melmed S, Polonsky KS, Larsen PR Eds/Williams Text book of endoclinicinology 12th Edition Philadelphia,Sander. Eleveier ;2011:chap 10.
[2]Verkman AS, Aquaporins in clinical medicine. Annu Rev Med.2012;63:303-16 (Medline)
[3]Stone KA, Lithium induced nephrogenic diabetes Insipidus.  J Am Board Fam Pract. 1999 Jan-Feb;12(1):43-7
[4]Babey M, Kopp P, Robertson GL. Familial forms of diabetes insipidus: clinical and molecular characteristics. at Rev. Endocrinol. 2011Jul 5; 7(12): 701-14. (Medline).
[5]Di Iorgi N, Napoli F, Allegeri AE, Ilivieri I, Bertelli E, Gallizia A, et al . Diabetes insipidus – Diagnosis and management. Horm Res Paediatr. 2012;77(2):69-84. (Medline).
[6]Trepiccione F, Christensen BM. Lithium induced nephrogenic diabetes Insipidus: new clinical and experimental finding.  J Nephrol Nov-Dec 2010-23 Suppl 16:S43-8 (Medline)
[7]Hadjizacharia P, Beale EO, Inaba K, et al. Acute diabetes Insipidus in severe head injury:  a prospective study. J.Am Coll Surg. At 2008;207(4):477-84 (Medline)
[8]Fenske W. Allolio B. Current Stale and future perspective in the diagnosis of Diabetic Insipidus : A clinical review J. Clin Endocrinol  Metab 2012 Oct;97(10):3426-37.  242 Aug 1.
[9]Hannon MJ, Sherlock M, Thompson CJ, Pituitary dysfunction following traumatic brain injury or sub- Arachnoid hemorrhage in “Endocrine management in the ICU” Best pract Res Clin endocrinal  Metab. Oct-2011;25(5):783-98 (Medline)
[10]Vande Walle J, Stockner M, Raes A, Norgaard JP.  Desompressin 30 years in clinical use: a safety review. Curr Drug saf. Sep 2007 ;2(3):232-8
[11]Ananthkrishana  S. Diabetes insipidus is pregnancy: etiology evaluation and management. Endo pract 2009 May-  Jun; 15(4):377-82
[12]n.margenthaler@brahms.de   PMD18291667 (pubmed for Medline)