Prospecting for antimicrobial substances produced in four species of ants

International Journal of Medical Science

© 2020 by SSRG - IJMS Journal

Volume 7 Issue 6

Year of Publication : 2020

Authors : Moroh Jean-Luc Aboya, Karamoko Detto, Kokora Aya Philomène, N’dri Ahou Roselyne, Koné Mouhamadou, Tornan Moussa Soro,Angoratchi Ebaley Marius, Coulibaly Adama

10.14445/23939117/IJMS-V7I6P103

How to Cite?

Moroh Jean-Luc Aboya, Karamoko Detto, Kokora Aya Philomène, N’dri Ahou Roselyne, Koné Mouhamadou, Tornan Moussa Soro,Angoratchi Ebaley Marius, Coulibaly Adama, "Prospecting for antimicrobial substances produced in four species of ants," SSRG International Journal of Medical Science, vol. 7,  no. 6, pp. 9-15, 2020. Crossref, https://doi.org/10.14445/23939117/IJMS-V7I6P103

Abstract:

Nowadays, we are witnessing the growth of difficult-to-treat infectious diseases caused by bacteria resistant to antibiotics. This resistance is most often caused by the misuse and improper use of antibiotics in both humans and animals. To remedy this problem, humans have turned to new sources of production of antibiotic molecules.
In this study, we focused on ants. It consisted in screening antimicrobial compounds from substances produced by ants and their microbiome. Four species of ants were used namely Paltothyreus tarsatus, Dorylus nigricans, Oecophylla longinoda, and Camponotus maculatus. First, successive extractions with three solvents (water, ethanol, dichloromethane) were carried out with the 4 species of ant. Only dichloromethane extracts from 3 ants, namely Dorylus nigricans, Oecophylla longinoda, and Camponotus maculatus, showed antimicrobial activity against Escherichia coli, Staphylococcus aureus and Candida albicans with minimum inhibitory concentrations (MIC) varying from 3 μg / ml to 15 μg / ml. Then, counting the microbiome of ants allowed 43 microorganisms to be isolated. Among them, two yeasts isolated from Camponotus maculatus showed antagonistic activity vis-à-vis Candida albicans.
these antimicrobial substances produced by these ants and their microbiota could be exploited as antibiotics or as precursors of antibiotics human and veterinary health

Keywords:

Antibiotic Resistance, Ants, Microbiome, antagonistic activity and antimicrobial activity

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