Comparative Effectiveness of Silver Sulphadiazine and Beta-Sitosterol Ointment as Dressings for Second Degree Burns

International Journal of Medical Science

© 2020 by SSRG - IJMS Journal

Volume 7 Issue 12

Year of Publication : 2020

Authors : Radwan A. Dalloul, Laith Kamal Zaid, Ahamad A. Oqlat

10.14445/23939117/IJMS-V7I12P102

How to Cite?

Radwan A. Dalloul, Laith Kamal Zaid, Ahamad A. Oqlat, "Comparative Effectiveness of Silver Sulphadiazine and Beta-Sitosterol Ointment as Dressings for Second Degree Burns," SSRG International Journal of Medical Science, vol. 7,  no. 12, pp. 5-7, 2020. Crossref, https://doi.org/10.14445/23939117/IJMS-V7I12P102

Abstract:

Aim: The purpose of this study was to investigate the comparative effectiveness of 1.0% silver sulphadiazine and 0.25% beta-sitosterol ointment as dressings for second-degree burns.
Methodology: This study was conducted at King Abdullah University Teaching Hospital in Irbid, Jordan, from May to November 2020. All participants were healthy patients with no known chronic medical conditions. All included patients had second-degree burns on any part of their body, not more than 2% of their total body surface area. Burns were analyzed for signs of infection, granulation formation, size reduction, and scar formation.
Results: 0.25% beta-sitosterol ointment overall showed better therapeutic results compared with 1.0% silver sulphadiazine cream. In particular, beta-sitosterol demonstrated better prevention of wound infection and increased granulation formation.
Conclusion: The quest for the most effective burn therapy will continue to focus on the formulation of preparations that enhance tissue regeneration and act as antimicrobial agents. This study suggests that beta-sitosterol ointment may be a better burn treatment than – and serve as a valuable alternative to – traditional therapies such as silver sulphadiazine, particularly where wound infection is not a primary concern.

Keywords:

Beta-sitosterol, burn wounds, ointment, silver sulphadiazine, ointment

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