The Prognostic Value of (NLR) Ratio in Patients with COVID-19

International Journal of Medical Science

© 2022 by SSRG - IJMS Journal

Volume 9 Issue 6

Year of Publication : 2022

Authors : Pauline Alkhoury, Malek Hejazie, Firas Hussain

10.14445/23939117/IJMS-V9I6P101

How to Cite?

Pauline Alkhoury, Malek Hejazie, Firas Hussain, "The Prognostic Value of (NLR) Ratio in Patients with COVID-19," SSRG International Journal of Medical Science, vol. 9,  no. 6, pp. 1-10, 2022. Crossref, https://doi.org/10.14445/23939117/IJMS-V9I6P101

Abstract:

Coronavirus disease 2019, COVID-19, has worried the world since the beginning of its spread and posed a threat to public health. An elevated NLR is an independent risk factor for death in covid-19. This study aims to highlight the importance of the high NLR in predicting the severity of the disease and severe clinical outcomes. A cohort study included 203 patients diagnosed with COVID-19 by CT chest and swab positivity PCR technique. The primary follow-up endpoint considered death, and the secondary was the need for intensive care or invasive or non-invasive mechanical ventilation . We performed a cut-off ROC curve for the NLR to predict poor prognosis in COVID-19 patients regarding death, need for mechanical ventilation or intensive care . The NLR was statistically significantly higher in patients who died or required intensive care and mechanical ventilation compared with patients who did not require intensive care or survived. We found that age, smoking, ischemic heart disease, chronic lung disease, NLR and CURB 65 are statistically significant and independent factors in predicting the need for mechanical ventilation and the prognosis of death in patients with COVID . The most sensitive inflammatory indicator for predicting death was the NLR. The best cut-off point for the NLR was also determined. It is the point with the highest sensitivity and specificity for predicting a lousy prognosis, NLR = 9.5, where the sensitivity is 70% and the specificity is 65%.

Keywords:

Covid-19 disease, Neutrophils, Lymphocytes, Death, Mechanical ventilation, NLR.

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