The Effect of Antipsychotic Drugs on Salivary Flow Rate and Dental Caries in Schizophrenic Patients
| International Journal of Medical Science |
| © 2023 by SSRG - IJMS Journal |
| Volume 10 Issue 3 |
| Year of Publication : 2023 |
| Authors : Atiyah Hasin, Mozammal Hossain, Anwar Parvez Bhuiyan, Md. Ali Asgor Moral |
10.14445/23939117/IJMS-V10I3P102
How to Cite?
Atiyah Hasin, Mozammal Hossain, Anwar Parvez Bhuiyan, Md. Ali Asgor Moral, "The Effect of Antipsychotic Drugs on Salivary Flow Rate and Dental Caries in Schizophrenic Patients," SSRG International Journal of Medical Science, vol. 10, no. 3, pp. 7-14, 2023. Crossref, https://doi.org/10.14445/23939117/IJMS-V10I3P102
Abstract:
This study sought to ascertain how antipsychotics affected patients with schizophrenia's salivary flow and risk of dental caries. 24 individuals with recently diagnosed schizophrenia who were given antipsychotic medication by a licensed psychiatrist made up the study population. Patients with schizophrenia who are on first-generation antipsychotic medications make up 12 participants, while patients with schizophrenia who are taking second-generation antipsychotic medications make up another 12 participants. Participants' oral health status was assessed using the decay index/missing/filled teeth (DMFT) and salivary flow rate. The results of this study indicate that in the first-generation group, 50.0% of patients were hydrated for 30 to 60 seconds, 66.7% of patients had foamy or bubbly saliva, 50% of patients had a PH of 6.0 to 6.8, and the mean salivation rate was 0.13 ± 0.06 milliliters per minute. In the second-generation group B, the mean salivation rate was 0.24 ± 0.09 (ml/min), 66.7% of patients had frothy or bubbly saliva, 66.7% had saliva with a PH of 6.8–7.8, and 58.3% had hydration 30 seconds. In terms of DMFT, 41.6 and 41.7% of patients in both groups they have had DMFT 0 at day zero. The DMFT score of zero, however, rapidly reduced in the second-generation group while remaining constant in the first-generation group. At 12 months, the variations in DMFT between the two groups were statistically significant (P <0.005). In conclusion, 2nd generation drug recipients with schizophrenia had much better oral health than the 1st generation group.
Keywords:
Schizophrenia, Dental problem, 1st generation drug, 2nd generation drug, DMFT.
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