Study of the Association Between Cerebral Venous Thrombosis and Inflammatory Biomarkers
| International Journal of Medical Science |
| © 2023 by SSRG - IJMS Journal |
| Volume 10 Issue 5 |
| Year of Publication : 2023 |
| Authors : Mary Kalaweez, Issa Layka, Firas Hussein |
10.14445/23939117/IJMS-V10I5P102
How to Cite?
Mary Kalaweez, Issa Layka, Firas Hussein, "Study of the Association Between Cerebral Venous Thrombosis and Inflammatory Biomarkers," SSRG International Journal of Medical Science, vol. 10, no. 5, pp. 6-11, 2023. Crossref, https://doi.org/10.14445/23939117/IJMS-V10I5P102
Abstract:
CVT is a relatively rare but serious type of stroke that affects young ages. Evidence is currently mounting on the role of inflammation in CVT. The research aims to study the relationship between inflammatory markers and CVT at the onset of thrombosis to determine the possibility of using these markers as a laboratory tool for the correct approach to diagnosis. Methods: A prospective cohort study was conducted between January 2021 and January 2023, in which the sample size consisted of 28 patients having CVT and 28 controls not suffering from CVT, with a statistical power of 95%. Intravenous samples were taken to conduct the following laboratory analyzes (Neutrophils – Lymphocytes – Platelets – CRP – ESR –NLR - PLR). Previous laboratory analyzes were compared between cases and controls and then analyzed statistically. Results: When comparing the ages of patients between the cases and controls, we did not find a statistically significant difference between the two groups, and the P-value was 0.980, as we found in our study a statistically significant difference between the two groups in terms of the values of the following laboratory analyzes (Neutrophils- Lymphocytes- Platelets -CRP - ESR – NLR- PLR), as the P-value reached the following 0.034 0.000-0.003-0.000-0.000-0.003-0.000, respectively. Conclusion: Our study confirmed the role of inflammation in the occurrence of cerebral venous sinus thrombosis and found that NLR, PLR, CRP and ESR can be used in clinical practice as a laboratory tools for predicting the diagnosis regardless of the etiology because they are inexpensive and widely available parameters.
Keywords:
Cerebral venous sinus thrombosis CRP, ESR, Inflammatory Markers, NLR, PLR.
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