Acute Drug Poisoning among Children Attending a Pediatric Emergency Department in Tishreen University Hospital
International Journal of Medical Science |
© 2024 by SSRG - IJMS Journal |
Volume 11 Issue 2 |
Year of Publication : 2024 |
Authors : Layal Issa, Souad Sakkour |
How to Cite?
Layal Issa, Souad Sakkour, "Acute Drug Poisoning among Children Attending a Pediatric Emergency Department in Tishreen University Hospital," SSRG International Journal of Medical Science, vol. 11, no. 2, pp. 1-5, 2024. Crossref, https://doi.org/10.14445/23939117/IJMS-V11I2P101
Abstract:
Background: Poisoning poses a significant challenge to public health, ranking among the foremost contributors to worldwide mortality, morbidity, and healthcare costs. Objective: This study aims to assess the incidence of pharmacological poisoning in pediatric patients, along with the eventual outcomes observed. Materials and Methods: A one-year crosssectional descriptive-analytical investigation was carried out from January 2022 to December 2022 at Tishreen University Hospital located in Lattakia, Syria. The study included all children attending emergency departments that care for children with a history of acute poisoning by drugs. Results: 228 children were analyzed, with 105 (46.1%) diagnosed with acute drug poisoning. The mean age was 3.24±2.1 years, and the most common age group was 1-4 years (81.9%). Males accounted for 49.5% of the sample, and females 50.5%. Respiratory drugs were the most frequently involved (21%), followed by psychotropic drugs (17.1%) and cardiovascular drugs (10.5%). Most cases (93.3%) were unintentional, with 39% occurring in the morning. Gastrointestinal ingestion was common (95.2%), with half during the winter and minimal parental intervention (90.5%). Circulatory and neurological symptoms were prevalent on admission (13.3% and 11.4%, respectively). Conclusion: There is an important prevalence of unintentional poisoning in the targeted health center, so taking prevention strategies for poisoning is considered crucial to improving the final outcome.
Keywords:
Children, Pharmacological, Poisoning, Prevalence, Syria.
References:
[1] Abdelrahman Ahmed et al., “Poisoning Emergency Visits Among Children: A 3-year Retrospective Study in Qatar,” BMC Pediatrics, vol. 15, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[2] Maribeth C. Lovegrove et al., “Trends in Emergency Department Visits for Unsupervised Pediatric Medication Exposures, 2004-2013,” Pediatrics, vol. 136, no. 4, pp. 821-829, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[3] Vincent R. Lee, Michael Connolly, and Diane P. Calello, “Pediatric Poisoning by Ingestion: Developmental Overview and Synopsis of National Trends,” Pediatric Annals, vol. 46, no. 12, pp. 443-448, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[4] G. Randall Bond, Randall W. Woodward, and Mona Ho, “The Growing Impact of Pediatric Pharmaceutical Poisoning,” The Journal of Pediatrics, vol. 160, no. 2, pp. 265-270, 2012.
[CrossRef] [Google Scholar] [Publisher Link]
[5] Lee M. Hampton et al., “Cough and Cold Medication Adverse Events After-market Withdrawal and Labeling Revision,” Pediatrics, vol. 132, no. 6, pp. 1047-1054, 2013.
[CrossRef] [Google Scholar] [Publisher Link]
[6] Maryann Mazer-Amirshahi et al., “Effect of Cough and Cold Medication Restriction and Label Changes on Pediatric Ingestions Reported to United States Poison Centers,” The Journal of Pediatrics, vol. 163, no. 5, pp. 1372-1376, 2013.
[CrossRef] [Google Scholar] [Publisher Link]
[7] M. Bull et al., “Academy of Pediatrics. Committee on Injury and Poison Prevention. Transporting Children with Special Health Care Needs,” Pediatrics, vol. 104, no. 4, pp. 988-992, 1999.
[Google Scholar] [Publisher Link]
[8] Lindsey C. Burghardt et al., “Adult Prescription Drug Use and Pediatric Medication Exposures and Poisonings,” Pediatrics, vol. 132, no. 1, pp. 18-27, 2013.
[CrossRef] [Google Scholar] [Publisher Link]
[9] Lucie Cluver et al., “Child and Adolescent Suicide Attempts, Suicidal Behavior and Adverse Childhood Experiences in South Africa: A Prospective Study,” Journal of Adolescent Health, vol. 57, no. 1, pp. 52-59, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[10] Henry A. Spiller et al., “Sex- and Age-specific Increases in Suicide Attempts by Self-Poisoning in the United States among Youth and Young Adults from 2000 to 2018,” The Journal of Pediatrics, vol. 210, pp. 201-208, 2019.
[CrossRef] [Google Scholar] [Publisher Link]
[11] Keith Henry, and Carson R. Harris, “Deadly Ingestions,” Pediatric Clinic, vol. 53, no. 2, pp. 293-315, 2006.
[CrossRef] [Google Scholar] [Publisher Link]
[12] Maneesha Agarwal et al., “Circumstances Involved in Unsupervised Solid Dose Medication Exposures among Young Children,” The Journal of Pediatrics, vol. 219, pp. 188-195, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Jessica Graham et al., “Illicit Drug Exposures in Young Pediatric Patients Reported to the National Poison Data System, 2006-2016,” The Journal of Pediatrics, vol. 219, pp. 254-258, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[14] Tais F. Galvao et al., “Economic Evaluation of Poison Centers: A Systematic Review,” International Journal of Technology Assessment in Health Care, vol. 28, no. 2, pp. 86-92, 2012.
[CrossRef] [Google Scholar] [Publisher Link]
[15] Maribeth C. Lovegrove et al., “Emergency Hospitalizations for Unsupervised Prescription Medication Ingestions by Young Children,” Pediatrics, vol. 134, no. 4, pp. 1009-1016, 2014.
[CrossRef] [Google Scholar] [Publisher Link]
[16] Nagesh Borse, and David A. Sleet, “CDC Childhood Injury Report: Patterns of Unintentional Injuries Among 0-19 Year Old in the United States, 2000-2006,” Family and Community Health, vol. 32, no. 2, pp. 189, 2009.
[CrossRef] [Publisher Link]
[17] Jennifer A. Lowry, Michele Burns, and Diane P. Calello, “Pediatric Pharmaceutical Ingestions,” Pediatric Annals, vol. 46, no. 12, pp. 459-465, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[18] David D. Gummin et al., “2020 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 38th Annual Report,” Clinical Toxicology, vol. 59, no. 12, pp. 1282-1501, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[19] Giovanni N. Berta et al., “Childhood Acute Poisoning in the Italian North –West Area: A Six-year Retrospective Study,” Italian Journal of Pediatric, vol. 46, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[20] Yura Ko et al., “Impact of Drug Formulation on Outcomes of Pharmaceutical Poisoning in Children Aged 7 Years or Younger,” Medicine (Baltimore), vol. 100, no. 40, p. e27485, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[21] Sultan Alghadeer et al., “The Patterns of Children Poisoning Cases in Community Teaching Hospital in Riyadh, Saudi Arabia,” Saudi Pharmaceutical Journal, vol. 26, no. 1, pp. 93-97, 2018.
[CrossRef] [Google Scholar] [Publisher Link]
[22] Tharwat El Zahran et al., “Toxicological Exposures Among the Pediatric Patients at a Tertiary Care Center in Lebanon: The Case for Establishing a Neonatal Poison Center,” Clinical Toxicology, vol. 59, no. 9, pp. 780-785, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[23] Sabiha Sahin, Kursat Bora Carman, and Ener Cagri Dinleyici, “Acute Poisoning in Children; Data of a Pediatric Emergency Unit,” Iranian Journal of Pediatric, vol. 21, no. 4, pp. 479-484, 2011.
[Google Scholar] [Publisher Link]
[24] Zeinab Abd Elmohdy Abd –Elhaleem, and Badar AbdulMohsen Al-Muqhem, “Pattern of Acute Poisoning in Al Majmaah Region, Saudi Arabia,” American Journal of Clinical and Experimental Medicine, vol. 2, no. 4, pp. 79-85, 2014.
[Google Scholar]