Prehypertension: A study in 18-20 year age group

International Journal of Medical Science

© 2016 by SSRG - IJMS Journal

Volume 3 Issue 8

Year of Publication : 2016

Authors : Abhay Kumar Pandey and Abha Pandit

10.14445/23939117/IJMS-V3I8P102

How to Cite?

Abhay Kumar Pandey and Abha Pandit, "Prehypertension: A study in 18-20 year age group," SSRG International Journal of Medical Science, vol. 3,  no. 8, pp. 5-10, 2016. Crossref, https://doi.org/10.14445/23939117/IJMS-V3I8P102

Abstract:

Background: Youth of 18 to 20 year age range making successfully to medical college admission represent struggling lot. Genotype, phenotype and environmental interactions that drive cardiovascular and other lifestyle diseases may be recognized meaningfully at such stage. Early detection of disease and its determinents can guide timely interventions and correction toward prevention/reduction of morbidity and mortality in modern lifestyle maladies Objective: Screening of first year medical student male and female subjects for prehypertension and their comparative study with normotensive peers in particular regard to family history, clinicodemographic and biochemical charecteristics Method: 23 subjects (16 males and 7 females) in 18- 20 year age range found to be prehypertensive upon screening were studied in comparison with 15 mached normotensive peers(10 males and 5 females). Familial, psychological behavioural, clinicodemographic and biochemical parameters were examined do define relevant associated trait of prehypertension. Result: History of maternal hypertension was significant determinant of prehypertension. Dietary and physical activity profiles did not differ but psychologic morbidity was more prevalent in prehypertensives as opposed to the normotensives. Overweight/obesity and activation of sympathetic nervous system were particularly associated with prehypertension group. Hyperinsulinaemia and insulin resistance was significantly associated while changes in lipid profile and level of inflammatory marker homocystein did not differ statistically significantly in prehypertensive group versus the normotensive controls. Conclusion: Screening ar early age is sound approach to unravel prehypertension and metabolic syndrome, specially in subjects with family history of such disorders. Detection of risk factors would help their timely modification for prevention/reduction of full grown disease.

Keywords:

Familial cardiovascular disease; prehypertension; metabolic syndrome; resting heart rate; homocystein

References:

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