EuroSCORE overestimated cardiac surgery related mortality: Comparing EuroSCORE model and Bayesian approach using new generalized probabilistic model with new form of prior information
International Journal of Medical Science |
© 2016 by SSRG - IJMS Journal |
Volume 3 Issue 12 |
Year of Publication : 2016 |
Authors : Jamal A. Al-Saleh, Satish K. Agarwal and Rashed Al-Bannay |
How to Cite?
Jamal A. Al-Saleh, Satish K. Agarwal and Rashed Al-Bannay, "EuroSCORE overestimated cardiac surgery related mortality: Comparing EuroSCORE model and Bayesian approach using new generalized probabilistic model with new form of prior information," SSRG International Journal of Medical Science, vol. 3, no. 12, pp. 1-7, 2016. Crossref, https://doi.org/10.14445/23939117/IJMS-V3I12P101
Abstract:
Objectives: An attempt is made to suggest an alternative approach using Bayesian analysis in predicting the mortality during cardiac surgery. The risk index predicted through Bayesian approach is compared with the traditional approach EuroSCORE Model for known data sets available in the internet [see [4]]. Methods: The overall mortality related to cardiac surgery was traced from 2002 to 2012.The data was extracted from the official blue book website of the Society for Cardiothoracic Surgery in Great Britain & Ireland. The cohort included patients who underwent cardiac surgery in NHS hospital and other private hospitals in U.K. During each year, the true mortality, predicted mortality by EuroSCORE, and estimated mortality through Bayesian approach were compared. Results: Overall mortality rates derived from EuroSCORE Model were much higher (more than double) of true reported mortality rate for the period 2006 to 2012, and almost 60% higher for the period 2003 to 2005, than the true mortality reported by the Society for Cardiothoracic Surgery in Great Britain & Ireland in its official website. While the Bayesian approach predicted mortality rates estimates that are more consistent, significantly lower than the one estimated by EuroSCORE, and much closer to the reported true mortality. Conclusions: Mortality rate post-surgery is considered a quality metric to hospitals. Bayesian approach provides greater advantage over EuroSCORE in predicting mortality post cardiac surgery. Both are noticed to overestimate the real surgical risk, being less with the Bayesians. Bayesian approach is an alternative predictor to estimate mortality post cardiac surgery and should be verified by further research.
Keywords:
Bayesian Analysis, Cardiac Surgery Activity, Data Analysis, EuroSCORE Model, Markov Chain Monte Carlo, Mortality Rate, Informative Prior.
References:
[1] Au WK , Sun MP, Lam KT, Cheng LC, Chiu SW and Das SR. Mortality prediction in adult cardiac surgery patients: comparison of two risk stratification models, Hong Kong Med J;13:pp 293-97, 2007.
[2] Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative riskevaluation (EuroSCORE). Eur J Cardiothorac Surg;pp16:9-13, 1999.
[3] Parsonnet, V., Dean D and Bernstein AD. A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. Circulation;79:pp I3- I12, 1989.
[4] EuroSCOR website (online) at http://bluebook.scts.org [5] Gelman A., Carlin JB., SternHS. and Rubin D.B. Bayesian data analysis. 2nd edition. Chapman and Hall/CRC. Boca Raton, FL; pp 696l 2004.
[6] http://www.va.gov/opa/feature/amervet/video/amvet2011- 6-7. asx
[7] Sensi L, Tedesco D, Mimmi S, Rucci P, Pisano E, et al. Hospitalization Rates and Post-Operative Mortality for Abdominal Aortic Aneurysm in Italy over the Period 2000– 2011. PLoS ONE, 8:12, 2013.
[8] Andrews LC, Special Functions of Mathematics for Engineers, Oxford University Press, Oxford, UK. 1998.
[9] Gummert, J.F., Funkat, A., Osswald, B. et al. EuroSCORE overestimates the risk of cardiac surgery: results from the national registry of the German Society of Thoracic and Cardiovascular Surgery. Clin Res Cardiol, 98: 363, 2009.
[10] Sanon S, Lee V-V, Elayda MA, et al. Predicting Early Death after Cardiovascular Surgery by Using the Texas Heart Institute Risk Scoring Technique (THIRST). Texas Heart Institute Journal. 2013;40(2):156-162.
[11] Feng Li., R code webpage (online) at https: //github.com/fengli/flutils/blob/master/math/ghypergeo.