Cholelithiasis – Incidence and Risk factor comparison in hospitalised patients

International Journal of Medical Science
© 2017 by SSRG - IJMS Journal
Volume 4 Issue 3
Year of Publication : 2017
Authors : Hemchandra Singh Thoudam
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Hemchandra Singh Thoudam, "Cholelithiasis – Incidence and Risk factor comparison in hospitalised patients," SSRG International Journal of Medical Science, vol. 4,  no. 3, pp. 27-29, 2017. Crossref, https://doi.org/10.14445/23939117/IJMS-V4I3P106

Abstract:

Background:- Gallbladder stone disease (GSD) is a prevailing health problem. The incidence and risk factors are differently occurring at various regions. Objective:- To find out the incidence and risk factors in terms of gender, age, diabetes mellitus, and tropogeographical status of this region. Study setting and design:- It was a randomised study in the department of surgery, J.N. Institute of Medical Science, Imphal, Manipur. Duration of study:- December 2015 to December 2016 Material and methods:- All the patients admitted in surgical ward for elective cholecystectomy and newly diagnosed cases in the ward were the subject of study. All the 2066 patients admitted in surgical wards were taken as general study sample size. Total number of GSD was 807. Investigation:- 1. Routine examination of blood. 2. USG for all patients 3. MRCP and ERCP for the patients suspected to have associated with common bile duct problems Result:- Out of the 2066 patients admitted in female surgical wards, GSD constituted 802, having the incidence rate of 39%. Female preponderance is more than male and occurs most frequently in the age group of 30-40 years (26.3%). Seven cases of diabetes mellitus were detected in male where as it was nine in female accounting to total number of sixteen . Number of GSD patients in male and female were 249 and 558 respectively to have a total number of 807 out of 2066 surgical in patients. Eight and ninety years old cases of GSD were diagnosed in male age group as an occurrence in the extreme. No convincing customary food habit related information can be collected Conclusion:- Gall stone disease (GSD) remains a substantial health problem since years everywhere in the world. Detection and documentation of cases are on the rise as a result of modern technique GSD is multifunctional. There are many reports of risk factors such as tropogeographical, age, sex, obesity and diabetic mellitus. Here in this study gender equality is treated at par the general consensus (female preponderance is more ). Diabetes remains a matter of further evaluation as its association with GSD is unclear due to a minimal number of related cases. Association of social dietary components is also not clear and is an agenda for further evaluation.

Keywords:

  Prevalence of gall stone disease. Cholelithiasis and geographical variation. Gall stone and diabetes. Social food and gall stone

References:

[1] Bradford  G  Stone,  et  al.Impairment of gall bladder emptying in diabetes mellitus.Gastroanterology July 1988 vol. 95 (1) :170-176
[2] Chalman,  B.A., Wison,  I.R,  et   al.Prevalence of gall bladder disease in diabetes mellitus Digest   Dis   Sci  (1996)  41:2222-8 
[3] Diel  A  K  , Sugarek N  J  Clinical evaluation for gall stone disease :  Usefulness of  symptoms and signs in diagnosis .   Am J Med  1990 ;89  : 29-33
[4] Hisam A  Barakat ,  John W Carpenter  et al. Influence of obesity, Impaired glucose tolerance and NIDDM on LDL structure and composition :possible link between hyper insulinemia and atherosclerosis. Diabetes 1990 Dec ; 39 (12) : 1527-1533
[5]  IKart R  W.  Gall stone,  cholecystitis and diabetes.  Surg Gynecol  Obstet 1990  Dec,  171 (6) :528-32 
[6] Lynn  J  .   Bennion , M.D.  at al.   Effect of Diabetes mellitus on cholesterol metabolism in man N.  Engl   J  Med  1977 ; 296 ... 1365-1371
[7] M. P.  Sharma Gall stone in north India J  Clin  Gastroenterol 1990 Oct ; 12(5) : 547 – 9
[8] Richard   E  . Sampliner  , M.D,  Gall bladder disease in Pima Indians – Demonstration of High prevalence and early onset by  cholecystography   N.Engl  J  Med 1970 ; 283:1358 1364 
[9] Sayeed  Unisa,  et  al.Population based study to  estimate prevalence and determine risk factors of gall bladder disease in rural Gangetic basin of north India HPB (Oxford ) 2011 Feb , 13 (2)..  117  -125
[10] Tanno  N  ,  Koizumi   M   et   al.Relationship between cholelithiasis and diabetes mellitus.. Discussion of age, obesity, hyper lipidemia  and  neuropathy Tohoku  J   Exp   Med   .  1988  Jan;154(1) .. 11-20