Effect of Kalonji (N. Sativa) Seeds on Glycemic Control of Patients with Type-2 Diabetes

International Journal of Medical Science

© 2017 by SSRG - IJMS Journal

Volume 4 Issue 3

Year of Publication : 2017

Authors : Shafi M. Shaafi and Harish Kulkarni

10.14445/23939117/IJMS-V4I3P108

How to Cite?

Shafi M. Shaafi and Harish Kulkarni, "Effect of Kalonji (N. Sativa) Seeds on Glycemic Control of Patients with Type-2 Diabetes," SSRG International Journal of Medical Science, vol. 4,  no. 3, pp. 36-40, 2017. Crossref, https://doi.org/10.14445/23939117/IJMS-V4I3P108

Abstract:

The effects of Kalonji (Nigella sativa) on glycemic control and management of newly diagnosed diabetic-2patients was evaluated in this study. The effect of N. Sativa on glycated hemoglobin (HbA1c), fasting blood sugar (FBS), postprandial blood Sugar (PPBS) was examined. Material & Methods: One hundred patients were randomly divided into two groups (n=50 each). Group-1: patients were advised metformin 500 mg twice a day & atorvastatin 10 mg once a day for a period of eight weeks. Group-2: N. Sativa (NS) patients were advised recommended doses of N. Sativa (NS) in addition to the medication in group-1. Aspirin 150 mg was given in both group 1 & 2. Basal FBS, PPBS& HbA1c was measured at the beginning of the evaluation and once every 14 days during the study. Blood samples were collected before and after the intervention for lipid profile. Results: N. Sativa significantly lowered FBS, PPBS& HbA1c after 8 weeks. The NS group showed significant improvement regarding FBG, PPBG, HbA1c, and LDL-cholesterol. Conclusions: This study shows that it is appropriate to give N.Sativa to diabetes-2 patients with poor glycemic control along with the conventional medication. However, the physician need to observe for any long-term changes and modify the dose.

Keywords:

Nigella sativa, Diabetes-2, glycemic control, Glycated hemoglobin (HbA1C).

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