Evaluation of the Performance of Interferon Gamma Assays for the Diagnosis of Bovine Tuberculosis in Hanwoo beef cattle in Korea

International Journal of Veterinary Science

© 2020 by SSRG - IJVS Journal

Volume 6 Issue 1

Year of Publication : 2020

Authors : Dr. Shin-Seok Kang, Ms. Sezim Monoldorova, Dr. Jeongim Woo, Dr. Hyeon-Seop Byon, Professor Minsun Hong, Dr. Seung-Cheol Kim, Professor Bo-Young Jeon

10.14445/24550868/IJVS-V6I1P101

How to Cite?

Dr. Shin-Seok Kang, Ms. Sezim Monoldorova, Dr. Jeongim Woo, Dr. Hyeon-Seop Byon, Professor Minsun Hong, Dr. Seung-Cheol Kim, Professor Bo-Young Jeon, "Evaluation of the Performance of Interferon Gamma Assays for the Diagnosis of Bovine Tuberculosis in Hanwoo beef cattle in Korea," SSRG International Journal of Veterinary Science, vol. 6,  no. 1, pp. 1-5, 2020. Crossref, https://doi.org/10.14445/24550868/IJVS-V6I1P101

Abstract:

Bovine tuberculosis (TB) is a contagious disease, and leads to major economic losses in agriculture; therefore, implementation of efficient diagnosis is essential for the control of bovine TB. The performance of a newly licensed commercial interferon gamma assay, ID Screen Ruminant IFN- ELISA (ID Screen ELISA, ID-Vet) was evaluated against the single caudal fold tuberculin (SCFT) test, an official test for detecting bovine TB, compared to the TB feron ELISA (Bionote), for the detection of bovine TB in Hanwoo beef cattle in Korea. In a total of 543 Hanwoo beef cattle, 75 (13.8%) and 73 (13.4%) were found to be positive for bovine TB using the ID Screen ELISA and TB feron ELISA, respectively. These results were slightly higher than those obtained with the SCFT test (10.1%, 55 of 543); however, the differences were not significant. Using the SCFT test as a reference, the sensitivity of both ID Screen ELISA and TB feron ELISA was 67.3% (37 of 55) and their specificities were 96.2% (450 of 488) and 92.6% (470 of 488), respectively. Additionally, there was a significant correlation between ID Screen ELISA and TB feron ELISA for the detection of bovine TB in Hanwoo beef cattle (r = 0.98). In conclusion, the interferon gamma assays, ID Screen ELISA and TB feron ELISA, correlated well with the SCFT test, and both assays showed excellent correlation between two gamma interferon assay for detecting bovine TB in Hanwoo beef cattle.

Keywords:

Bovine tuberculosis (TB), interferon gamma assay, single caudal fold tuberculin (SCFT) test, Hanwoo beef cattle.

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