Synthesis, Charaterization And Antibacterial Studies of A Schiff Base Complex Derived From 2,4-Dinitrophenylhydrazine

International Journal of Applied Chemistry

© 2021 by SSRG - IJAC Journal

Volume 8 Issue 2

Year of Publication : 2021

Authors : Mukhtar Haruna, U.T. Joram

10.14445/23939133/IJAC-V8I2P104

How to Cite?

Mukhtar Haruna, U.T. Joram, "Synthesis, Charaterization And Antibacterial Studies of A Schiff Base Complex Derived From 2,4-Dinitrophenylhydrazine," SSRG International Journal of Applied Chemistry, vol. 8,  no. 2, pp. 12-16, 2021. Crossref, https://doi.org/10.14445/23939133/IJAC-V8I2P104

Abstract:

Some novel transition metal complexes of Co(II), and Ni(II) with Schiff-base derived from the condensation reaction of 2,4-dinitrophenylhydrazine and benzaldehyde were synthesized in alcoholic medium. The complexes were characterized on the basis of melting point, molar conductivity, solubility, IR and UV/Visible spectral studies. The infrared data revealed that the two ligands of 2,4-dinitrophenylhydrazine behaves as bidentate chelating agents coordinating through the oxygen and the nitrogen of the ligand. The ratio of the metal-ligand was found to be (2:1). The molar conductance values (17.70-10.25) showed that the complexes are non-electrolytes. In order to evaluate the effect of metal ions upon chelation, the Schiff bases and their complexes were screened for antibacterial activity against the strains such as Escherichia coli, Staphylococcus aureus, and Salmonella Typhi using the agar-well diffusion method. The synthesized Schiff base complexes exhibit higher antibacterial activity against the tested pathogens compared to the free Schiff base because of chelation. The infrared spectral analysis showed values ranging from 3250cm-1-3269cm-1 for u(N-H), 1604cm-1-1618cm-1 for u(C=N), 1330-1332cm-1 for u( ), 550-555cm-1 for u(M-N) and 450-520cm-1 for u(M-O) bands respectively.

Keywords:

Schiff bases, Metal complexes, Urea, Benzaldedyde, Microorganisms.

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